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Related Experiment Videos

Remnant liver function during surgery for extensive hepatic resection.

N Nagasue, K Inokuchi, A Iwaki

    The Japanese Journal of Surgery
    |June 1, 1979
    PubMed
    Summary
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    Evaluating remnant liver function (RLF) using indocyanine green (ICG) before liver resection helps predict post-operative outcomes. This method aids surgeons in determining resectability, especially in complex cases, to prevent hepatic failure.

    Area of Science:

    • Hepatobiliary Surgery
    • Surgical Oncology
    • Diagnostic Imaging

    Background:

    • Assessing functional liver reserve is crucial before hepatectomy.
    • Current methods may not accurately reflect conditions post-resection.
    • Predicting hepatic failure after extensive liver resection remains a challenge.

    Purpose of the Study:

    • To evaluate indocyanine green (ICG) for assessing remnant liver function (RLF) under pre-resection conditions.
    • To determine the utility of RLF measurement in guiding hepatectomy decisions.
    • To establish a reliable method for predicting hepatic failure post-liver resection.

    Main Methods:

    • Utilized temporary clamping of hepatic inflow vessels to simulate post-hepatectomy conditions.
    • Measured remnant liver function (RLF) using indocyanine green (ICG) in healthy dogs.

    Related Experiment Videos

  • Applied the RLF-ICG method in nine patients undergoing 40-70% hepatectomy.

    • Main Results:

    • In dogs, RLF-ICG accurately predicted hepatic failure after simulated extensive liver resection.
    • In patients, RLF-ICG measurements during surgery correlated with resectability.
    • The method proved reliable when performed under stable hemodynamic conditions.

    Conclusions:

    • Temporary vessel clamping combined with ICG is a valuable method for assessing RLF.
    • This technique aids in deciding resectability for hepatectomy, particularly in equivocal cases.
    • RLF assessment using ICG can help prevent post-operative hepatic failure.