Related Experiment Video
Updated: May 26, 2026
11:32
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
[Risk factors for recurrent pneumonia in children: a case-control study]
Yong-Li Zhao1, Zheng-Juan Liu, Yu-Chuan Wang
1Department of Pediatrics, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, China. zhaoyongli79@yahoo.com.cn
Summary
History of wheezing, allergies, and transient neutropenia are key risk factors for recurrent pneumonia in children without underlying diseases. Identifying these factors aids in preventing repeated pneumonia episodes.
Area of Science:
- Pediatric Pulmonology
- Immunology
Context:
- Recurrent pneumonia poses a significant health challenge in children.
- Identifying risk factors is crucial for effective prevention and management strategies.
- This study focuses on children without pre-existing underlying medical conditions.
Purpose:
- To investigate the risk factors associated with recurrent pneumonia in children lacking underlying diseases.
- To differentiate between children with single pneumonia episodes and those experiencing recurrent episodes.
Summary:
- A case-control study compared 106 children with recurrent pneumonia to 106 controls with single pneumonia episodes, all without underlying diseases.
- Wheezing history, allergic history (food/medicine), and transient neutropenia were significantly more prevalent in the recurrent pneumonia group.
- Multivariate logistic regression identified wheezing history (OR=13.39), allergic history (OR=4.27), and transient neutropenia (OR=3.61) as independent risk factors.
Impact:
- Findings highlight specific clinical indicators for increased risk of recurrent pneumonia.
- This knowledge can guide targeted interventions and monitoring for at-risk children.
- The study contributes to a better understanding of pneumonia recurrence in otherwise healthy children.
Related Concept Videos
01:30Pneumonia I: Introduction
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
01:29Pneumonia I: Introduction
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
01:30Pneumonia V: Nursing management and Prevention
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
01:26Factors Affecting the Risk of Infection
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
01:30Pneumonia III: Complications and Assessment
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
01:28Pneumonia IV: Management
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include: