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Published on: October 16, 2021
Watchful waiting for severe mitral regurgitation
1Department of Cardiology, Medical University of Vienna, Vienna, Austria. raphael.rosenhek@meduniwien.ac.at
Insights
Watchful waiting is a viable strategy for severe organic mitral regurgitation in asymptomatic patients, guided by clinical guidelines. Optimal outcomes depend on regular monitoring and timely surgery at expert centers.
Area of Science:
- Cardiology
- Cardiac Surgery
- Clinical Medicine
Background:
- Severe organic mitral regurgitation (OMR) management involves watchful waiting for asymptomatic patients.
- Current guidelines define surgical indications based on symptoms, left ventricular (LV) function, and LV size.
- The optimal timing for surgical intervention in asymptomatic patients with preserved LV function remains debated.
Purpose of the Study:
- To review the established strategy of watchful waiting for severe OMR.
- To discuss the current indications for surgical intervention in OMR.
- To highlight the importance of individualized decision-making in managing OMR.
Main Methods:
- Review of European Society of Cardiology and American Heart Association/American College of Cardiology guidelines.
- Analysis of clinical and echocardiographic follow-up strategies.
- Consideration of patient-specific factors and surgical risks.
Main Results:
- Watchful waiting is effective when patients are monitored clinically and echocardiographically.
- Surgery in expert centers leads to excellent outcomes.
- Early recognition and referral are crucial to avoid delayed treatment.
Conclusions:
- Watchful waiting, combined with periodic monitoring and timely surgery, offers excellent outcomes for severe OMR.
- Individualized treatment decisions considering disease natural history, surgical risk, and repair likelihood are paramount.
- Further research may clarify the role of surgery in asymptomatic patients with preserved LV function.
Abstract:
Watchful waiting is an established treatment strategy for asymptomatic patients with severe organic mitral regurgitation. It is based on indications for surgery that are based on current European Society of Cardiology and American Heart Association/American College of Cardiology guideline recommendations, which are defined by symptom onset, impairment of left ventricular function, and left ventricular enlargement. Excellent outcome is achieved when patients are periodically followed with clinical and echocardiographic examinations and when surgery is performed in expert centers. The strategy is based on the recognition of mitral regurgitation at an early symptomatic stage, avoiding a delayed referral of these patients. There is an ongoing debate about whether surgery should be performed in asymptomatic patients with preserved ventricular function. Ultimately, decision-making needs to be individualized and to take individual patient-related factors and local resources (including the natural history of the disease, the risk of surgery, and the likelihood of successful mitral valve repair) into consideration to obtain an optimal outcome with medical and surgical management.
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