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Updated: May 26, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
Parents' Internet use for information about HPV vaccine
Annie-Laurie McRee1, Paul L Reiter, Noel T Brewer
1Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 325 Rosenau Hall, CB 7440, Chapel Hill, NC 27599-7440, USA. almcree@email.unc.edu
Purpose:
The Internet is an increasingly common source of health-related information. We sought to examine associations between parents' Internet information-seeking and their knowledge, attitudes and beliefs about human papillomavirus (HPV) vaccine.
Methods:
We interviewed parents within a year after approval of HPV vaccine for females and males. Participants were North Carolina parents with daughters ages 10-18 surveyed by telephone in Fall 2007 (n=773); and a national sample of parents with sons ages 11-17 surveyed online in Fall 2010 (n=115). We used multivariate regression to examine associations of past and intended Internet seeking for HPV vaccine information with knowledge and health belief model-related constructs.
Results:
Among parents of daughters, having heard of HPV vaccine through the Internet (8%) was associated with higher HPV knowledge, perceived likelihood of HPV, and vaccination willingness, and with receiving a doctor's recommendation. It was also associated with lower perceived vaccine harms, uncertainty, and anticipated regret. Parents of sons who heard of HPV vaccine through the Internet (10%) perceived greater barriers to vaccination than parents who learned about HPV vaccine for males through other sources. Intended future Internet information-seeking among parents of daughters (69%) was more likely if they perceived a lower likelihood that their daughters would get HPV if they were vaccinated (all p<.05).
Conclusions:
Our findings suggest a positive influence of accessing information on the Internet about HPV vaccine. It was associated with higher knowledge and mostly positive parental attitudes and beliefs.
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