Related Experiment Video
Updated: May 26, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Fungal, Mycobacterial, and Nocardia infections and the eye: an update
1Cornea and Anterior Segment Services, LV Prasad Eye Institute, Banjara Hills, Hyderabad, India. prashant@lvpei.org
Abstract:
Although relatively uncommon, fungi, atypical Mycobacteria, and Nocardia have been isolated from a variety of infections of eye including keratitis, scleritis, canaliculitis, dacryocystitis, endophthalmitis and orbital cellulites. The organisms typically cause a slowly progressive disease. The diseases caused by the organisms can pose both diagnostic and therapeutic challenges. In this manuscript we will describe updates on important aspects of the ocular infections caused by these organisms.
Insights
Fungi, atypical mycobacteria, and Nocardia can cause uncommon but challenging eye infections like keratitis and endophthalmitis. This review updates key aspects of diagnosing and treating these slow-progressing ocular diseases.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Fungi, atypical mycobacteria, and Nocardia are uncommon causes of ocular infections.
- These pathogens can lead to various eye conditions, including keratitis, scleritis, and endophthalmitis.
- Infections caused by these organisms often present as slowly progressive diseases.
Purpose of the Study:
- To provide updated information on ocular infections caused by fungi, atypical mycobacteria, and Nocardia.
- To highlight the diagnostic and therapeutic challenges associated with these infections.
- To review important aspects of these specific microbial eye diseases.
Main Methods:
- Literature review of recent studies and case reports.
- Synthesis of current knowledge on epidemiology, clinical presentation, diagnosis, and management.
- Focus on updates and advancements in the field.
Main Results:
- These uncommon organisms cause a spectrum of ocular diseases.
- Diagnosis can be challenging due to slow progression and varied presentations.
- Therapeutic strategies require specific antimicrobial approaches and may be complex.
Conclusions:
- Ocular infections by fungi, atypical mycobacteria, and Nocardia require specialized diagnostic and treatment approaches.
- Staying updated on these rare but serious conditions is crucial for effective patient care.
- Further research may improve diagnostic accuracy and therapeutic outcomes.
Related Concept Videos
Microbiome of the Eye
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Fungal Phylum Microsporidia
Glaucoma: Overview
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
