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ACE gene sequence and nucleotide variants in IgA nephropathy.

K T Woo1, Y K Lau, C M Chan

  • 1Department of Renal Medicine, Singapore General Hospital, Outram Road, Singapore 169608. woo.keng.thye@sgh.com.sg

Singapore Medical Journal
|December 17, 2011
PubMed
Summary

Genetic variations in the angiotensin-converting enzyme (ACE) gene influence IgA nephropathy (IgAN) progression and response to treatment. Specific ACE gene alleles and haplotypes are linked to adverse or protective renal outcomes.

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