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Related Experiment Video

Updated: May 26, 2026

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation

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Portal vein embolization: what do we know?

Alban Denys¹, John Prior, Pierre Bize

¹Department of Radiology and Interventional Radiology Unit, Centre Hospitalo Universitaire Vaudois, Lausanne, Switzerland. Alban.Denys@chuv.ch

Cardiovascular and Interventional Radiology

|December 17, 2011

Summary

This summary is machine-generated.

Portal vein embolization (PVE) enhances future remnant liver (FRL) size before major liver resection, reducing postoperative liver insufficiency. This technique uses preoperative imaging to guide embolization, increasing FRL volume and function within weeks.

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Area of Science:

Hepatobiliary Surgery
Interventional Radiology
Surgical Oncology

Background:

Major hepatectomy for liver disease carries a risk of postoperative liver insufficiency.
Portal vein embolization (PVE) is a technique to increase the size of the future remnant liver (FRL).

Purpose of the Study:

To evaluate the efficacy of PVE in increasing FRL volume and function.
To assess the impact of PVE on reducing postoperative liver insufficiency.
To compare different PVE techniques regarding hypertrophy rate and procedural risk.

Main Methods:

Preoperative computed tomography (CT) to measure FRL volume and its ratio with total liver volume.
Embolization of portal branches supplying segments planned for resection.
Assessment of FRL volume and function increase 3-6 weeks post-PVE.
Evaluation of n-butyl-cyano-acrylate as an embolic agent.

Main Results:

PVE leads to significant increases in FRL volume and function within 3-6 weeks.
This hypertrophy permits extensive liver resections in patients previously contraindicated.
N-butyl-cyano-acrylate offers a favorable balance between hypertrophy and procedural risk.

Conclusions:

PVE is an effective strategy to augment FRL prior to major hepatectomy.
The technique mitigates the risk of liver insufficiency following extensive liver resections.
N-butyl-cyano-acrylate presents a promising option for PVE procedures.