Related Experiment Video
Updated: May 26, 2026
Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Graft selection in elderly patients undergoing coronary artery bypass grafting
Toshihiro Fukui1, Minoru Tabata, Shigefumi Matsuyama
1Department of Cardiovascular Surgery, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, Tokyo, 183-0003, Japan. tfukui-cvs@umin.ac.jp
Insights
Elderly patients (≥75 years) undergoing coronary artery bypass grafting (CABG) experienced similar clinical and angiographic outcomes compared to younger patients. This indicates that age is not a significant factor in CABG success rates.
Area of Science:
- Cardiovascular Surgery
- Geriatric Medicine
- Clinical Outcomes Research
Background:
- Coronary artery bypass grafting (CABG) is a common procedure for coronary artery disease.
- Assessing outcomes in elderly populations is crucial due to demographic shifts and increased prevalence of comorbidities.
Purpose of the Study:
- To evaluate and compare the clinical and angiographic results of CABG in elderly patients (≥75 years) versus non-elderly patients (<75 years).
Main Methods:
- A retrospective review of 1021 patients who underwent CABG.
- Patients were divided into two groups: elderly (≥75 years, n=292) and non-elderly (<75 years, n=729).
- Comparison of operative/postoperative variables and early/1-year graft patency rates.
Main Results:
- Elderly patients had higher rates of female sex, unstable angina, and congestive heart failure.
- Operative mortality and major complication rates were similar between groups.
- Early and 1-year graft patency rates were comparable in both elderly and non-elderly groups.
Conclusions:
- Clinical and angiographic outcomes after CABG in elderly patients are comparable to those in non-elderly patients.
- Age ≥75 years does not appear to be a significant predictor of adverse outcomes post-CABG.
Purpose:
This study aimed to assess the clinical and angiographic outcomes after coronary artery bypass grafting (CABG) in elderly patients (≥75 years).
Methods:
We reviewed the records of 1021 patients who underwent CABG between September 2004 and December 2009. We divided these patients into two groups: ≥75 years (group E, n = 292) versus <75 years (group N, n = 729). We compared operative and postoperative variables and early and 1-year angiographic patency rates of grafts between the groups.
Results:
The rates of female sex (P < 0.01), unstable angina (P = 0.04), and history of congestive heart failure (P < 0.01) were higher in group E than in group N. More patients in group N had diabetes (P = 0.03) and hyperlipidemia (P < 0.01) than those in group E. Operative mortality (1.0% in group E vs. 0.3% in group N; P = 0.14) and the rate of major complications were not significantly different between the groups. The mean number of anastomoses per patient was similar in the groups. The rate of left internal thoracic artery use was not significantly different between the groups, although the use of other arterial grafts was significantly higher in group N than in group E. There were no significant differences in the early (98.5% vs. 97.2%, P = 0.08) or 1-year (91.6% vs. 89.3%, P = 0.28) patency rates of all grafts in the groups.
Conclusion:
The clinical and angiographic outcomes after CABG in elderly patients were almost identical to those in nonelderly patients.
