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Informing our elders about dialysis: is an age-attuned approach warranted?
1Section of Nephrology, West Virginia University School of Medicine, 1 Medical Center Drive, Box 9165, Morgantown, WV 26506, USA. rschmidt@hsc.wvu.edu
Insights
Older adults with chronic kidney disease (CKD) may not benefit from dialysis due to age and comorbidities. Informed consent should be age-sensitive, discussing risks, benefits, and potential loss of independence.
Area of Science:
- Nephrology
- Geriatrics
- Bioethics
Background:
- Older adults are the fastest-growing segment of the end-stage renal disease (ESRD) population.
- These patients often have multiple comorbid conditions and unique needs impacting renal replacement therapy decisions.
- Dialysis may offer limited survival benefits and increased risks for older individuals with impaired functional status.
Purpose of the Study:
- To review medical evidence and guidelines for advance care planning in older CKD patients.
- To present considerations for discussions with older adults considering dialysis.
- To recommend an age-attuned approach to informed consent for dialysis in this population.
Main Methods:
- Review of medical evidence and clinical practice guidelines.
- Analysis of issues relevant to advance care planning and informed consent for older CKD patients.
- Development of recommendations for an age-sensitive informed consent process.
Main Results:
- Dialysis burdens and risks can be amplified in older patients, potentially negating survival benefits.
- Dialysis withdrawal rates are highest among the oldest patients.
- Standard informed consent may not adequately address the unique risk-benefit balance for older adults with comorbidities.
Conclusions:
- Informed consent for dialysis in older CKD patients requires an age-sensitive approach.
- Discussions should include age-specific prognosis, risks, benefits, burdens, and potential impact on independence and function.
- An age-attuned informed consent process is crucial for appropriate advance care planning.
Abstract:
As the fastest growing sector of the incident ESRD population, older patients constitute a group for which renal replacement therapy has special implications. Older CKD patients have unique needs by virtue of advanced age, high prevalence of comorbid conditions, slower progression of renal disease, and reduced survival. Burdens and risks attendant to dialysis may be amplified in the older patient and patients with impaired functional status or comorbid conditions, and therefore, dialysis may confer little to no survival benefit. Rates of dialysis withdrawal are highest among the oldest patients, raising the possibility that the standard content of informed consent for dialysis warrants an age-sensitive approach that is attuned to the very different balance of pros and cons of dialysis for older patients with multiple comorbidities and younger patients with limited comorbidity. Informed consent for older patients should include presentation of risks, benefits, and burdens associated with dialysis, age-specific estimates of prognosis with and without dialysis, and potential for loss of independence and decline in functional status with initiation of dialysis. In this article, medical evidence and clinical practice guidelines relevant to advance care planning for the older patient with CKD are reviewed, issues to consider in the dialogue with older patients contemplating dialysis are presented, and recommendations for an age-attuned approach to informed consent for older CKD patients are made.
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