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Whole Blood Assay with Dual Co-Stimulation for Antigen-Specific Analysis of Host Immunity to Fungal and Viral Pathogens
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Humoral HLA sensitization matters in CBT outcome
Marcelo A Fernandez-Vina1, Marcos de Lima, Stefan O Ciurea
1Stanford University; the University of Texas M.D. Anderson Cancer Center.
Blood
|December 17, 2011
Abstract:
In this issue of Blood, Cutler and colleagues present evidence that donor-specific anti-HLA antibodies are associated with graft failure in double umbilical cord blood transplantation (CBT).1 Engraftment of donor cells is the first important step in successful transplantation and, until recently, the causes of engraftment failure remained elusive.
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