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Updated: May 26, 2026
Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
Published on: March 11, 2016
Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients
Florian Seidensticker1, Aljoscha S Neubauer, Tamer Wasfy
1Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.
Background And Objectives:
Detection of peripheral fundus autofluorescence (FAF) using conventional scanning laser ophthalmoscopes (SLOs) is difficult and requires pupil dilation. Here we evaluated the diagnostic properties of wide-field FAF detected by a two-laser wavelength wide-field SLO in uveitis patients.
Study Design/Materials And Methods:
Observational case series of four patients suffering from different types of posterior uveitis/chorioretinitis. Wide-field FAF images were compared to visual fields. Panretinal FAF was detected by a newly developed SLO, which allows FAF imaging of up to 200° of the retina in one scan without the need for pupil dilation. Visual fields were obtained by Goldmann manual perimetry.
Results:
Findings from wide-field FAF imaging showed correspondence to visual field defects in all cases.
Conclusion:
Wide-field FAF allowed the detection of visual field defect-related alterations of the retinal pigment epithelium in all four uveitis cases.
