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Prevalence of retinopathy of prematurity in Latin America
Juliana Zimmermann Carrion1, João Borges Fortes Filho, Marcia Beatriz Tartarella
1Program for the Prevention of Blindness due to Retinopathy of Prematurity, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Insights
Retinopathy of prematurity (ROP) prevalence varies widely in Latin America, with inconsistent screening and treatment services. Different patient selection criteria hinder progress in understanding ROP trends.
Area of Science:
- Ophthalmology
- Neonatology
- Public Health
Background:
- Retinopathy of prematurity (ROP) is a significant cause of visual impairment in premature infants.
- Latin America faces challenges in ROP screening and treatment due to varying healthcare resources and protocols.
Purpose of the Study:
- To review ROP prevalence studies in Latin America over a decade (2000-2010).
- To assess improvements in ROP prevalence rates.
- To identify patient inclusion criteria for ROP screening programs.
Main Methods:
- Systematic review of 33 studies from ten Latin American countries published between 2000 and 2010.
- Analysis of reported ROP prevalence and severity.
- Examination of inclusion criteria for ROP screening.
Main Results:
- ROP prevalence ranged from 6.6% to 82%; severe ROP requiring treatment was 1.2% to 23.8%.
- Routine ROP screening and treatment services were lacking in many countries.
- Inconsistent inclusion criteria (birth weight and gestational age) impeded comparative analysis.
Conclusions:
- Variability in inclusion criteria hinders ROP trend analysis in Latin America.
- Restrictive screening criteria may not be suitable for all Latin American contexts.
- Inadequate data prevents determining if ROP prevalence has decreased.
Abstract:
The purpose of this work was to review the studies published over the last 10 years concerning the prevalence of retinopathy of prematurity (ROP) in Latin American countries, to determine if there was an improvement in ROP prevalence rates in that period, and to identify the inclusion criteria for patients at risk of developing ROP in the screening programs. A total of 33 studies from ten countries published between 2000 and 2010 were reviewed. Prevalence of any ROP stage in the regions considered ranged from 6.6% to 82%; ROP severe enough to require treatment ranged from 1.2% to 23.8%. There was no routine screening for ROP, and there was a lack of services for treatment of the disease in many countries. Inclusion criteria for patients in the studies ranged between birth weight ≤ 1500 g and ≤ 2000 g and gestational age ≤ 32 and <37 weeks. Use of different inclusion criteria regarding birth weight and gestational age in several Latin American studies hindered comparative analysis of the published data. Highly restrictive selection criteria for ROP screening in relation to birth weight and gestational age should not be used throughout most Latin American countries because of their different social characteristics and variable neonatal care procedures. The studies included in this review failed to provide adequate information to determine if the prevalence of ROP has decreased in Latin America.
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