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Updated: May 26, 2026

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
Cardiac surgery in patients with acute intermittent porphyria
Filippo Benassi1, Elena Righi, Paolo Cimato
1Department of Cardiovascular Surgery, Hesperia Hospital, Modena, Italy. filippo.benassi@libero.it
Abstract:
Acute intermittent porphyria (AIP) is a disorder of the heme biosynthesis pathway of a specific inherited enzymatic defect. Many different environmental factors such as drugs, calorie restriction, infection etc., often play a key role in triggering a porphiric acute attack. We describe a 50-year-old woman with AIP who underwent aortic valve replacement due to acute infective endocarditis and review the perioperative management of these patients.
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