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[Neuron-specific enolase in pleural effusions of various etiologies]
G Plavec1, A Lazarov, V Dangubić
1Klinika za plućne bolesti VMA, Beograd.
Plucne Bolesti : Casopis Udruzenja Pneumoftiziologa Jugoslavije = the Journal of Yugoslav Association of Phthisiology and Pneumology
|January 1, 1990
Abstract:
The concentration of neuron-specific enolase (NSE) was measured in the serum and pleural fluid of 42 patients with pleural effusions of different etiology. High levels (above 13.0 micrograms/l) of NSE in pleural fluid of 9 patients with malignant disease were observed (sensitivity 57%). However, pleural fluid NSE levels were also increased in 14 with non-malignant diseases (specificity 45%). Increased pleural fluid NSE activity is not specific for malignancy.