Delirium secondary to pregabalin

Area of Science:

• Neurology
• Pharmacology

Background:

• Fibromyalgia is a prevalent and debilitating condition requiring effective pain management.
• Pregabalin is an approved medication for fibromyalgia pain but carries risks of neuropsychiatric side effects.

Observation:

• Delirium secondary to pregabalin has been reported, typically in elderly patients with multiple health issues.
• This report details a case of delirium in a young patient with no significant prior medical conditions.

Findings:

• The young patient developed delirium without other contributing medications or comorbidities.
• Pregabalin was identified as the sole apparent cause of the delirium in this case.

Implications:

• Clinicians should consider pregabalin as a potential cause of delirium, even in younger patients.
• This case underscores the importance of evaluating medication side effects in unexplained delirium.