Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 26, 2026

Mouse Round Spermatid Injection
08:41

Mouse Round Spermatid Injection

Published on: January 26, 2024

Is intracytoplasmic sperm injection overused?

Brooke Hodes-Wertz1, Christine M Mullin, Alexis Adler

  • 1New York University Fertility Center, New York University School of Medicine, New York, NY, USA. hodesb01@med.nyu.edu

The Journal of Urology
|December 20, 2011
PubMed
Summary

Intracytoplasmic sperm injection (ICSI) use can be reduced in repeat IVF cycles without impacting pregnancy success. This suggests ICSI may be overused, and should be reserved for specific clinical indications.

Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Double embryo transfer with mosaic embryos: experience from a large academic fertility centre.

Reproductive biomedicine online·2026
Same author

Is planned oocyte cryopreservation delivering?

Reproductive biomedicine online·2025
Same author

The effects of age, mature oocyte number, and cycle number on cumulative live birth rates after planned oocyte cryopreservation.

Journal of assisted reproduction and genetics·2024
Same author

Maternal age at transfer following autologous oocyte cryopreservation is not associated with live birth rates.

Journal of assisted reproduction and genetics·2024
Same author

Planned oocyte cryopreservation: the state of the ART.

Reproductive biomedicine online·2023
Same author

Preimplantation genetic testing for monogenic disorders: clinical experience with BRCA1 and BRCA2 from 2010-2021.

Journal of assisted reproduction and genetics·2023

Area of Science:

  • Reproductive Medicine
  • In Vitro Fertilization (IVF)
  • Embryology

Background:

  • Intracytoplasmic sperm injection (ICSI) is a common technique in assisted reproductive technology.
  • Previous ICSI cycles performed elsewhere may lead to its repeated use without re-evaluation.

Purpose of the Study:

  • To assess if reducing ICSI usage in patients with prior ICSI cycles impacts pregnancy rates.
  • To determine if less stringent ICSI criteria affect fertilization and live birth rates.

Main Methods:

  • Retrospective analysis of 149 in vitro fertilization-embryo transfer cycles.
  • Comparison between an all insemination group and a half insemination/half ICSI group for patients with prior ICSI.
  • Evaluation of fertilization, implantation, clinical pregnancy, and live birth rates.

More Related Videos

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes
08:59

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes

Published on: October 5, 2016

Related Experiment Videos

Last Updated: May 26, 2026

Mouse Round Spermatid Injection
08:41

Mouse Round Spermatid Injection

Published on: January 26, 2024

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes
08:59

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes

Published on: October 5, 2016

Main Results:

  • Similar fertilization rates between the all insemination (74%) and half ICSI (73%) groups.
  • In the half ICSI group, 69% of inseminated and 78% of ICSI-oocytes were fertilized.
  • No statistically significant difference in live birth rates was observed between the groups.

Conclusions:

  • Applying stricter criteria for ICSI does not compromise clinical outcomes in repeat IVF cycles.
  • Adequate fertilization can be achieved with or without ICSI.
  • ICSI may be overutilized and should be reserved for clinically validated indications.