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Hyper-activated motility in sperm capacitation is mediated by phospholipase D-dependent actin polymerization

Sarit Bar-Sheshet Itach1, Maya Finklestein, Nir Etkovitz

  • 1The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University Ramat-Gan, 52900, Israel.

Developmental Biology
|December 20, 2011
PubMed
Summary

Phospholipase D (PLD)-dependent actin polymerization is crucial for sperm motility during capacitation. This process is essential for sperm to fertilize an egg, enabling hyper-activated motility (HAM) and the acrosome reaction (AR).

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