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Updated: May 26, 2026

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
[Impact of tobacco on bronchopulmonary affections: magnitude of the problem]
Leila El Fekih1, Anissa Berraies, Agnes Hamzaoui
1Hopital Aberrrahman Mami, Ariana, Tunisie.
Background:
Tobacco smoking is frequent in the world affecting 20 à 50% of the population but with a decrease in occidental countries due to a huge effort based on sensiblisation and anti-tobacco decisions.
Aim:
To review the impact of tobacco on bronchopulmonary affections.
Methods:
A narrative review of literature
Results:
In the next future, yearly tobacco-related deaths could increase from 4.2 millions in 2000 to 10 millions in 2025-2030 making smoking as the main evitable cause of deaths by respiratory diseases. Lung cancer is the leading killer cancer. Tobacco is the most frequent cause of respiratory diseases. It is responsible of 80 to 90% of deaths by chronic obstructive pneumobronchopathiy (COPD) and 80 to 85% deaths by bronchopulmonary cancer.
Conclusion:
Tobacco is a « chronic disease » necessitating management with advices and medical treatment.
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