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Updated: May 26, 2026

A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium
Published on: May 18, 2021
[Steatosis in chronic hepatitis C: prevalence and predictive factors]
Asma Ouakaa-Kchaou1, Dalila Gargouri, Asma Kochlef
1Departement de Gastro-enterologie, Hopital Habib Thameur, Tunis, Tunisie.
Background:
Patients with hepatitis C virus seem to often have hepatic steatosis.
Aim:
To assess the prevalence and the predictive factors of steatosis during chronic hepatitis C.
Methods:
We studied 50 HCV RNA positive subjects, who had liver biopsy performed. Steatosis was searched and patients were divided into to groups according to the presence or not of steatosis.
Results:
On liver biopsy, 28 patients (56%) had steatosis. Multivariante analysis showed that steatosis was associated with age 58 years > 1,1 μmol/l, odds ratio 2 (95% CI 1.48 - 2.6; p= 0.02) and triglycerides level, odds ration 4,22 (95% CI 1.05 - 16.98; p = 0,03.
Conclusion:
In this study, steatosis was significantly associated with metabolic factors.
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