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Updated: May 26, 2026
Low-cost Custom Fabrication and Mode-locked Operation of an All-normal-dispersion Femtosecond Fiber Laser for Multiphoton Microscopy
Published on: November 22, 2019
First clinical results with a new 200 kHz femtosecond laser system
Christoph Winkler von Mohrenfels1, Ramin Khoramnia, Josefina Salgado
1Augenklinik Klinikum rechts der Isar, Technische Universität München, Munich, Germany. christoph.wvm@gmail.com
Background:
The aim of this study was to perform the first femtosecond laser cuts with a new prototype femtosecond laser, in vivo and to evaluate its safety, stability and efficacy.
Methods:
A LASIK cut was performed with a prototype 200 kHz femtosecond laser in both eyes of nine patients and one eye of two patients (20 individual eyes in total). A complete ophthalmic examination was performed preoperatively and postoperatively at 1, 3, 6 and 12 months after the procedure.
Results:
In the pilot series of 20 eyes, flap creation was possible in each case. The mean preoperative manifest refractive spherical equivalent was À-4.22 D (SD ± 61.22 D). The postoperative spherical equivalent refraction was À-0.1 D (SD ± 60.26 D) at 1 month, À-0.22 D (SD ± 60.24 D) at 3 months and À-0.15 D (SD ± 60.16 D) 12 months after surgery.
Conclusions:
Femto-LASIK with this new laser system showed high levels of safety, stability and efficacy without any enhancement.
Clinical Trials Registration:
http://www.dimdi.de. DE/CA126/AP4/3332/27/09. Bfam registration 09/03/2009, DE/CA126.
