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Updated: May 26, 2026

Single-Molecule Diffusion and Assembly on Polymer-Crowded Lipid Membranes
Published on: July 19, 2022
Translocation properties of copolymer (A(n)B(m))(l) through an interacting pore
Li-Zhen Sun1, Wei-Ping Cao, Meng-Bo Luo
1Department of Physics, Zhejiang University, Hangzhou 310027, China.
Abstract:
The translocation of a copolymer (A(n)B(m))(l) through an interacting pore was investigated by Monte Carlo simulation on a three-dimensional cubic lattice. Interactions between monomer A and pore ɛ(A) and between monomer B and pore ɛ(B) were considered. The difference between two translocation orientations, orientation A with monomer A entering the pore first and orientation B with monomer B first, was studied. Both the orientation probability and translocation time are dependent on monomer-pore interactions, block length, and fractions of monomers. The separation of different copolymers using translocation was also discussed. The results were explained qualitatively from the view of the free energy landscape of the copolymer translocation.
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