Related Experiment Video
Updated: May 26, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Removing the need for crossmatched blood in elective EVAR
1Frimley Park Hospital NHS Foundation Trust, Portsmouth Road, Frimley, Surrey, UK. dr.kmann@gmail.com
For elective endovascular aneurysm repair (EVAR), a type and screen is sufficient due to a low transfusion rate. This approach reduces costs and waste, as intraoperative transfusions are rarely needed.
Area of Science:
- Vascular Surgery
- Transfusion Medicine
- Health Economics
Background:
- The cost of crossmatching blood is significant (£137.22 per unit).
- A standardized maximum surgical blood order schedule for elective endovascular aneurysm repair (EVAR) is lacking.
- High crossmatch to transfusion (C:T) ratios can lead to unnecessary blood wastage and increased costs.
Purpose of the Study:
- To determine the crossmatch to transfusion ratio for elective EVAR.
- To establish a recommendation for a maximum surgical blood order schedule for elective EVAR.
- To assess the feasibility of using a type and screen protocol for elective EVAR.
Main Methods:
- A retrospective study of 203 consecutive elective EVAR cases from October 2001 to December 2010.
- Analysis of blood loss, units transfused, and indications for transfusion.
- Calculation of the crossmatch to transfusion ratio.
Main Results:
- Median blood loss was 200 ml (mean 288 ml).
- Only 6% of patients required blood transfusion, with most transfusions for postoperative low hemoglobin or medical complications.
- The crossmatch to transfusion ratio was 11.1, indicating a high rate of crossmatched blood units not transfused.
Conclusions:
- A 'group and save' (type and screen) protocol is recommended for elective EVAR due to the high C:T ratio.
- Intraoperative transfusions are infrequent (<1%) but can be massive, necessitating emergency protocols.
- Implementing this strategy can lead to significant financial savings, improved efficiency, and reduced blood wastage across surgical specialties.
More Related Videos
11:59Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
Published on: September 6, 2017
08:43Isolation of Endothelial Progenitor Cells from Healthy Volunteers and Their Migratory Potential Influenced by Serum Samples After Cardiac Surgery
Published on: February 14, 2017
Related Concept Videos
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Blood Typing
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Rh Blood Group