Is pertussis in infants a potential cause of retinal haemorrhages?

Ana Isabel Curcoy1, Victoria Trenchs, Marta Morales

  • 1Emergency Department, Sant Joan de Deu Hospital, passeig Sant Joan de deu 2 08950, Barcelona, Spain. acurcoy@hsjdbcn.org

Insights

Retinal hemorrhages are not caused by pertussis (whooping cough) in infants. This study found no cases of retinal hemorrhages in infants hospitalized with pertussis, suggesting it

Area of Science:

  • Pediatrics
  • Ophthalmology
  • Infectious Diseases

Background:

  • Retinal hemorrhages in infants can be indicative of abusive head trauma.
  • Differentiating abusive head trauma from other medical conditions is crucial.

Purpose of the Study:

  • To determine the prevalence of retinal hemorrhages in infants diagnosed with pertussis.
  • To aid in the differential diagnosis of abusive head trauma in infants.

Main Methods:

  • Prospective study of 35 children aged 15 days to 2 years with pertussis.
  • Ophthalmological examinations conducted within 72 hours of hospital admission.
  • Further investigations to rule out systemic disorders or maltreatment if hemorrhages were detected.

Main Results:

  • No retinal hemorrhages were observed in any of the 35 children with pertussis.
  • The upper limit for the prevalence of retinal hemorrhages due to symptomatic pertussis requiring hospitalization was estimated at 9.9% (95% confidence).

Conclusions:

  • Pertussis infection is unlikely to be a cause of retinal hemorrhages in children under two years of age.
  • This finding helps in excluding pertussis as a cause when evaluating retinal hemorrhages in infants.
Abstract

Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...