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Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine
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Nutrient detection by incretin hormone secreting cells.

Eleftheria Diakogiannaki1, Fiona M Gribble, Frank Reimann

  • 1Cambridge Institute for Medical Research and Department of Clinical Biochemistry, Addenbrooke's Hospital, Cambridge, UK.

Physiology & Behavior
|December 21, 2011
PubMed
Summary

This review explores how gut cells detect nutrients to release incretin hormones like glucagon-like peptide-1 (GLP-1) and glucose-dependent insulintropic polypeptide (GIP). Understanding these mechanisms could lead to new diabetes treatments by enhancing the incretin effect.

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