Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Introduction to Hemostasis01:05

Introduction to Hemostasis

Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Extrinsic and Intrinsic Pathways of Hemostasis01:20

Extrinsic and Intrinsic Pathways of Hemostasis

Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
Vascular Spasm01:16

Vascular Spasm

The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last for...
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FGFR2 Regulates Liver Injury and Repair in a Model of Obstructive Jaundice.

Frontiers in bioscience (Landmark edition)·2026
Same author

The association between ejaculatory dysfunction and lumbosacral disorders: a systematic review of an underrecognized clinical link.

Sexual medicine reviews·2026
Same author

Mechanical thrombectomy for acute ischemic stroke secondary to left atrial myxoma combined with lower-extremity arterial embolism: a case report.

AME case reports·2026
Same author

Piezocatalytic nanotransducers rewire tumor immunometabolism via in situ peroxynitrite generation.

Biomaterials·2026
Same author

Self-adaptive nanozymes with enhanced multi-enzyme activities for sequential multimodal therapy of drug-resistant bacteria-infected wounds.

Nature communications·2026
Same author

Genetic dissection of cadmium accumulation in tea plants under nonphytotoxic field conditions.

Journal of genetics and genomics = Yi chuan xue bao·2026

Related Experiment Video

Updated: May 26, 2026

Integrated Compensatory Responses in a Human Model of Hemorrhage
07:57

Integrated Compensatory Responses in a Human Model of Hemorrhage

Published on: November 20, 2016

Heating pad for the bleeding: external warming during hemorrhage improves survival.

Ying Wang1, Jianhua Feng, Guoxing You

  • 1Institute of Transfusion Medicine, Academy of Military Medical Sciences, Beijing, China.

The Journal of Trauma
|December 21, 2011
PubMed
Summary

Warming rats during hemorrhagic shock helped maintain body temperature and blood pressure, significantly improving survival rates. This suggests active warming is beneficial in managing shock victims.

More Related Videos

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma
04:20

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma

Published on: July 28, 2020

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

Related Experiment Videos

Last Updated: May 26, 2026

Integrated Compensatory Responses in a Human Model of Hemorrhage
07:57

Integrated Compensatory Responses in a Human Model of Hemorrhage

Published on: November 20, 2016

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma
04:20

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma

Published on: July 28, 2020

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

Area of Science:

  • Physiology
  • Medical Research

Background:

  • Hypothermia is a common complication during hemorrhagic shock.
  • The efficacy of therapeutic warming in shock management remains debated.
  • This study addresses the controversy by examining warming's effects on physiological parameters and survival.

Purpose of the Study:

  • To investigate the impact of therapeutic warming during the initial phase of hemorrhage.
  • To assess the effects of warming on body temperature, blood pressure, and survival in a rat model of hemorrhagic shock.

Main Methods:

  • Forty rats were divided into control (no heating) and warming (37°C) groups.
  • Hemorrhage was induced by withdrawing 40% of total blood volume over 60 minutes.
  • Rectal temperature, mean arterial pressure (MAP), and survival were recorded at multiple time points.

Main Results:

  • Warming group maintained higher rectal temperatures and MAP compared to controls throughout hemorrhage (p < 0.05).
  • Survival rates were significantly higher in the warming group (p < 0.01).
  • Both groups showed gradual decreases in temperature and MAP during blood loss.

Conclusions:

  • Therapeutic warming during hemorrhage mitigates hypothermia and hypotension.
  • Active warming improves survival outcomes in hemorrhagic shock models.
  • Findings support the use of warming interventions in managing shock patients.