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Successful double bypass in a patient with severe hemophilia A: a case report
Giovanni Barillari1, Samantha Pasca, Filippo Erice
1Center for Hemorrhagic and Thrombotic Diseases, University Hospital of Udine, P.le S. Maria della Misericordia, 15, 33100, Udine, Italy.
Abstract:
Life expectancy in the hemophilia people is similar to the non-haemophilics and age-related cardiovascular disorders to become more prevalent, but cardiac surgery is considered a very high risk for these patients. In this article we report the successful cardiac double bypass internal mammary artery--coronary artery in a patient with severe hemophilia A. (FVIII<1%; missense mutation: exon 16, c.5508 G>A (domain A3), p.Trp1817Stop). Continuous infusion of rFVIII B-domain deleted was used to control haemostasis during surgery and in post-operative period. There was no bleeding complications and the patient did not need to receive transfusion of red blood cells or platelets.