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Updated: May 26, 2026
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A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
New infarct exclusion repair using cohesive double-patch closer.
Shinya Takahashi1, Naomichi Uchida, Katsuhiko Imai
1Department of Surgery, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. shiny@mte.biglobe.ne.jp
Interactive Cardiovascular and Thoracic Surgery
|December 21, 2011
Summary
Ventricular septal perforation (VSP) is a serious myocardial infarction complication. A novel double-patch closure with infarct exclusion offers a successful treatment for VSP.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Ventricular septal perforation (VSP) is a life-threatening complication following acute myocardial infarction.
- Despite advancements, VSP management remains challenging, often requiring complex surgical interventions.
Observation:
- A patient presented with VSP subsequent to a posterior wall myocardial infarction.
- The clinical scenario necessitated an effective and minimally invasive treatment approach.
Findings:
- A new, simple surgical technique involving double-patch closure combined with infarct exclusion was successfully employed.
- This method achieved VSP closure and infarct exclusion without compromising the left ventricular cavity volume.
Implications:
- This innovative procedure presents a promising alternative for managing VSP post-myocardial infarction.
- The technique's simplicity and efficacy suggest potential for broader clinical application in cardiac repair.
