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Updated: May 26, 2026

A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
New infarct exclusion repair using cohesive double-patch closer
Shinya Takahashi1, Naomichi Uchida, Katsuhiko Imai
1Department of Surgery, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. shiny@mte.biglobe.ne.jp
Abstract:
Ventricular septal perforation (VSP) is a serious complication of acute myocardial infarction despite improved procedures for closing the ventricular septal wall defect and/or excluding the infarct. The patient in the present case had VSP after posterior wall infarction and was treated successfully with a new and simple procedure that used a double-patch closure combined with an infarct exclusion technique. The left ventricular patch was attached cohesively to the septal wall and the infarcted area was excluded without reducing the left ventricular cavity.

