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Published on: May 23, 2021
[The susceptibility of Proteus mirabilis strains isolated from white stork (Ciconia ciconia)]
Joanna Kwiecińska-Piróg1, Tomasz Bogiel, Eugenia Gospodarek
1Katedra i Zakład Mikrobiologii, Collegium Medicum im. L. Rydygiera w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu.
Abstract:
Proteus sp. rods are ubiquitous bacteria, widespread in the environment and classified also as opportunistic human pathogens. The aim of our study was to evaluate susceptibility of Proteus mirabilis strains isolated from white stork (Ciconia ciconia) regarding as his natural bacterial flora, compare and discuss their results with data obtained from scientific literature for clinical strains of the same species. Susceptibility of 59 P. mirabilis strains was estimated for 27 antimicrobials using disc-diffusion method and the ability to produce extended spectrum beta-lactamases was evaluated by double disc synergy test. Environmental P. mirabilis strains isolated from white stork were assessed as more susceptible to most of the examined antimicrobials and production of extended spectrum beta-lactamases was not noted amongst them.
Insights
Environmental Proteus mirabilis strains from white storks show higher antimicrobial susceptibility. Extended-spectrum beta-lactamase production was not detected in these bacterial isolates.
Area of Science:
- Microbiology
- Environmental Science
- Veterinary Medicine
Background:
- Proteus mirabilis are ubiquitous bacteria found in the environment.
- These bacteria are also opportunistic human pathogens.
- Understanding their prevalence and resistance patterns is crucial for public health.
Purpose of the Study:
- To evaluate the antimicrobial susceptibility of Proteus mirabilis strains isolated from white storks (Ciconia ciconia).
- To compare these findings with clinical strains of P. mirabilis from scientific literature.
- To assess the prevalence of extended-spectrum beta-lactamase (ESBL) production in these environmental isolates.
Main Methods:
- Antimicrobial susceptibility testing of 59 P. mirabilis strains using the disc-diffusion method against 27 antimicrobials.
- Evaluation of extended-spectrum beta-lactamase production using the double disc synergy test.
Main Results:
- Proteus mirabilis strains isolated from white storks demonstrated greater susceptibility to most tested antimicrobials.
- No extended-spectrum beta-lactamase production was observed in the environmental P. mirabilis strains.
- Significant differences in antimicrobial resistance profiles were noted when compared to clinical strains.
Conclusions:
- Environmental Proteus mirabilis from white storks represent a distinct population with generally lower antimicrobial resistance.
- The absence of ESBL production in these strains suggests a lower immediate risk for the spread of such resistance genes.
- Further research is needed to understand the ecological role and potential transmission dynamics of these bacteria.
