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Related Concept Videos

Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Oogenesis01:22

Oogenesis

Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Folliculogenesis01:20

Folliculogenesis

Folliculogenesis is the development of ovarian follicles, the specialized structures within the ovarian cortex where oogenesis, or egg development, occurs. This process is essential for female reproductive health and begins during fetal development when primordial follicles are formed. Each primordial follicle comprises a primary oocyte in the center, surrounded by a single layer of squamous pre-granulosa cells. These follicles remain dormant in late prophase I of meiosis until triggered by...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
Ovaries01:26

Ovaries

The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of cuboidal...

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Related Experiment Video

Updated: May 26, 2026

Production and Use of Customizable Agarose Molds for Scaffold-Free Mouse Ovarian Follicle Culture
09:50

Production and Use of Customizable Agarose Molds for Scaffold-Free Mouse Ovarian Follicle Culture

Published on: October 24, 2025

[Ovary: ontogenesis and aging].

E A Morozova, N S Lin'kova, V O Poliakova

    Advances in Gerontology = Uspekhi Gerontologii
    |December 22, 2011
    PubMed
    Summary

    This review examines the neuroendocrine control of ovarian development and aging. It highlights the crucial role of ovarian immune cells in reproductive system aging processes.

    Area of Science:

    • Reproductive Biology
    • Endocrinology
    • Immunology

    Background:

    • The ovary is the primary reproductive organ, and its development and aging are complex processes.
    • Neuroendocrine mechanisms significantly influence ovarian function throughout life.
    • Involutive processes in the reproductive system involve changes in ovarian function.

    Purpose of the Study:

    • To review the neuroendocrine mechanisms governing ovarian development and aging.
    • To analyze new research on the role of ovarian immune cells in reproductive aging.

    Main Methods:

    • Literature review of neuroendocrine mechanisms in ovarian development and aging.
    • Analysis of recent studies investigating immune cell involvement in ovarian involution.

    More Related Videos

    Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
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    Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome

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    Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice
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    Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice

    Published on: February 12, 2018

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    Last Updated: May 26, 2026

    Production and Use of Customizable Agarose Molds for Scaffold-Free Mouse Ovarian Follicle Culture
    09:50

    Production and Use of Customizable Agarose Molds for Scaffold-Free Mouse Ovarian Follicle Culture

    Published on: October 24, 2025

    Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
    12:25

    Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome

    Published on: February 24, 2023

    Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice
    06:49

    Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice

    Published on: February 12, 2018

    Main Results:

    • Neuroendocrine factors are central to the developmental and aging trajectories of the ovary.
    • Immune cells within the ovary play a significant role in the aging process of the reproductive system.

    Conclusions:

    • Understanding the interplay between neuroendocrine systems and ovarian immunity is crucial for comprehending reproductive aging.
    • Further research into ovarian immune cell function can provide insights into age-related reproductive decline.