Laparoscopic versus open peritoneal dialysis catheter insertion, the LOCI-trial: a study protocol

Area of Science:

• Nephrology
• Surgical Innovation
• Medical Device Technology

Background:

• Peritoneal dialysis (PD) is a vital treatment for end-stage renal disease, offering patients greater autonomy than hemodialysis.
• Successful PD relies on a well-functioning dialysis catheter, with complications potentially leading to loss of access.
• Current PD catheter insertion techniques vary, potentially impacting complication rates.

Purpose of the Study:

• To compare laparoscopic versus open PD catheter insertion techniques.
• To minimize the incidence of catheter malfunction at 6 weeks postoperatively.
• To evaluate the impact of insertion technique on patient quality of life.

Main Methods:

• A multi-center, randomized controlled, single-blind pilot trial (LOCI-trial).
• Comparison of laparoscopic versus open PD catheter insertion.
• Assessment of catheter malfunction and quality of life.

Main Results:

• Literature suggests lower catheter failure rates with laparoscopic (13%) versus open (35%) techniques.
• This trial aims to provide robust evidence to confirm these findings.
• Further analysis will detail specific complication rates and functional outcomes.

Conclusions:

• Evidence is needed to determine the optimal PD catheter insertion technique.
• This study will elucidate the benefits of laparoscopic over open PD catheter insertion.
• Findings will inform clinical practice and improve patient outcomes in PD.