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Updated: May 26, 2026

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Intraductal Delivery to the Rabbit Mammary Gland
Published on: March 9, 2017
Breast-feeding and benign breast disease
S Bernardi1, A P Londero, S Bertozzi
1Department of Surgery, AOU SM della Misericordia, Udine, Italy
Summary
Breast-feeding duration did not differ significantly across benign breast disease (BBD) types. However, lactation duration correlated with the number of fibroadenomas, suggesting a potential influence on this common BBD.
Area of Science:
- Reproductive Medicine
- Oncology
- Epidemiology
Background:
- Benign breast disease (BBD) is highly prevalent in women of reproductive age.
- The relationship between BBD and reproductive factors, particularly breast-feeding, requires further elucidation.
Purpose of the Study:
- To investigate the association between benign breast disease and breast-feeding history.
- To explore if lactation influences the occurrence or type of BBD.
Main Methods:
- A case-control study involving 105 women with BBD and 98 controls.
- Data collection focused on reproductive history and breast-feeding duration.
- Statistical analysis performed using R, with significance set at p < 0.05.
Main Results:
- Fibroadenoma was the most common BBD (55%).
- No significant difference in breast-feeding duration was observed between BBD groups and controls.
- A direct correlation was found between breast-feeding duration and the number of fibroadenomas in affected women (p < 0.05).
Conclusions:
- While overall breast-feeding patterns do not differ across BBD types, lactation duration may positively influence the development of fibroadenomas.
- Further prospective research is recommended to confirm the link between lactation and benign breast conditions.
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