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Updated: May 26, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Successful smoking cessation with electronic cigarettes in smokers with a documented history of recurring relapses: a
Pasquale Caponnetto1, Riccardo Polosa, Cristina Russo
1Centro per la Prevenzione e Cura del Tabagismo (CPCT), Dipartimento di Biomedicina Clinica e Molecolare, Azienda Ospedaliero-Universitaria "V, Emanuele-Policlinico", Università di Catania, Catania, Italy. p.caponnetto@unict.it.
Introduction:
Smoking cessation programs are useful in helping smokers to quit, but smoking is a very difficult addiction to break and the need for novel and effective approaches to smoking cessation interventions is unquestionable. The E-cigarette is a battery-powered electronic nicotine delivery device that may help smokers to remain abstinent during their quit attempt. We report for the first time objective measures of smoking cessation in smokers who experimented with the E-cigarette.
Case Presentation:
Three Caucasian smokers (two men aged 47 and 65 years and one woman aged 38 years) with a documented history of recurring relapses were able to quit and to remain abstinent for at least six months after taking up an E-cigarette.
Conclusions:
This is the first time that objective measures of smoking cessation are reported for smokers who quit successfully after using an E-cigarette. This was accomplished in smokers who repeatedly failed in previous attempts with professional smoking cessation assistance using the usual nicotine dependence treatments and smoking cessation counselling.
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