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Updated: May 26, 2026

A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice
Published on: May 10, 2013
[Optimization of creatinine measurement for laboratory estimation of glomerular filtration rate]
Ruth Da Silvera-Martínez1, Ramón Jiménez-Gutiérrez
1Unidad de Medicina Familiar 34, Instituto Mexicano del Seguro Social, Jalisco, México. rdasilvera@hotmail.com
Objective:
to analyze the optimization of serum creatinine in the laboratory reports of the estimation of glomerular filtration rate (GFR) in groups of patients who were overweight, obese, hypertensive, or had participated in SOHDI diabetes self-help groups. We also looked at how much the patients had learned about their disease, stress control, diet and exercise, as all the problems have increased risk of kidney disease.
Methods:
The serum creatinine results in the Family Medicine Unit No. 34, IMSS, at Jalisco, was analyzed in a transverse study, from January to December of 2008. GFR was estimated with the Cockcroft-Gault formulary. Statistical analysis with multivariate logistic regression analyses was performed.
Results:
the sample was 8331 patients: 23.5 % with GFR < 60 mL/min/1.73 m(2), and 9.1 % with serum creatinine > 1.5 mg/dL. Associated factors were age < 19 years, woman age 19 to 59 years, and SOHDI.
Conclusions:
the study suggested that participating in SOHDI groups, and being women are protective factors for dimunution of GFR. The people < 19 years had lesser GFR.
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