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Related Concept Videos

Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.

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Related Experiment Video

Updated: May 26, 2026

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
14:52

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Published on: January 13, 2018

Substance abuse in anaesthetists.

Roser Garcia-Guasch1, Jaume Roigé, Jaume Padrós

  • 1Anaesthesiology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. rosergg@hotmail.com

Current Opinion in Anaesthesiology
|December 22, 2011
PubMed
Summary

Anesthesiologists show significantly higher rates of substance abuse compared to other physicians. This review examines the contributing factors and ongoing efforts to address this critical issue in the medical field.

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Last Updated: May 26, 2026

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
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08:49

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention

Published on: October 16, 2013

Area of Science:

  • Medical Science
  • Physician Health

Background:

  • Anesthesiologists exhibit a substance abuse rate nearly three times higher than other physicians.
  • Physician addiction remains a persistent and significant concern within the medical community.

Purpose of the Study:

  • To review the elevated frequency of substance abuse among anesthesiologists.
  • To explore current hypotheses and debates surrounding anesthesiologist susceptibility to addiction.
  • To discuss institutional and programmatic efforts to combat physician substance abuse.

Main Methods:

  • Review of existing literature and hypotheses on anesthesiologist substance abuse.
  • Analysis of factors contributing to increased susceptibility.
  • Examination of ongoing debates regarding return-to-work policies for dependent physicians.
  • Overview of developed physician health programs and institutional strategies.

Main Results:

  • Multiple hypotheses exist, including genetic predisposition, stress, co-occurring psychopathology, and environmental/second-hand exposure.
  • Environmental exposure and sensitization are considered significant risk factors for addiction.
  • Debates continue regarding the rehabilitation and return to practice for anesthesiologists with opioid dependence.

Conclusions:

  • Substance abuse among anesthesiologists persists, necessitating ongoing research into susceptibility factors.
  • Development and implementation of clear substance abuse policies and control measures are crucial globally.
  • Physician health programs and institutional support are vital in addressing this issue.