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pH-changes during intracoronal bleaching: an in vivo study.

Daphne Camara Barcellos1, Alessandra Buhler Borges, Regina Celia dos Santos Pinto Silva

  • 1Department of Restorative Dentistry, São Josédos Campos School of Dentistry, São Paulo State University, São Paulo, Brazil.

The Journal of Contemporary Dental Practice
|December 22, 2011
PubMed
Summary

Intracoronal bleaching agents, hydrogen peroxide/sodium perborate and carbamide peroxide/sodium perborate, maintained alkaline pH over 14 days. However, hydrogen peroxide showed a significant pH reduction, suggesting careful consideration for clinical application.

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Area of Science:

  • Endodontics
  • Dental Materials Science
  • Biochemistry

Background:

  • Intracoronal bleaching is a common treatment for discolored endodontically treated teeth.
  • Hydrogen peroxide and carbamide peroxide are widely used bleaching agents.
  • Sodium perborate is often used as an activator in intracoronal bleaching.

Purpose of the Study:

  • To measure and compare pH changes over 14 days for two intracoronal bleaching agents.
  • To evaluate the safety of hydrogen peroxide/sodium perborate and carbamide peroxide/sodium perborate pastes based on pH alterations.

Main Methods:

  • Twenty patients with discolored endodontically treated central maxillary incisors were divided into two groups (n=10).
  • Group 1 received a 37% carbamide peroxide + sodium perborate paste (CP + SP).

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  • Group 2 received a 30% hydrogen peroxide + sodium perborate paste (HP + SP).
  • pH values were measured at baseline, 2, 7, and 14 days using a digital microprocessor.
  • Statistical analysis involved two-way ANOVA and Tukey's test.

    • Main Results:

    • Both bleaching agent combinations exhibited alkaline pH values throughout the 14-day study period.
    • A statistically significant reduction in pH was observed for the 30% hydrogen peroxide + sodium perborate group after 14 days (pH 7.98 ± 0.58).
    • The carbamide peroxide + sodium perborate group maintained a more stable alkaline pH (ranging from 8.89 to 9.66).

    Conclusions:

    • Both intracoronal bleaching agent associations demonstrated alkaline pH, indicating potential safety.
    • The significant pH decrease in the hydrogen peroxide group warrants further investigation regarding long-term effects.
    • Carbamide peroxide/sodium perborate may offer a more stable pH profile during intracoronal bleaching.