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Updated: May 26, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
Pain levels after third molar surgical removal: an evaluation of predictive variables
Marcelo Carlos Bortoluzzi1, Andre Guollo, Diogo L Capella
1Department of Stomatology and Maxillofacial Surgery, School of Dentistry, Oeste de Santa Catarina University, Av. Getúlio Vargas 2125-Bairro Flor da Serra-Joaçaba, Santa Catarina, Brazil. mbortoluzzi@gmail.com
Aim:
The aim of this prospective study was to evaluate the pain course after surgical removal of third molars.
Materials And Methods:
The sample consisted of 100 consecutive patients. Pain intensity was assessed by means of a visual analog scale (VAS).
Results:
At day 1, moderate and severe pain were observed predominantly in patients who had surgery in the mandible (p < 0.001) and for patients younger than 24 years (p = 0.009), while more patients who weekly consumed mate tea (Ilex paraguariensis) showed pain classified as none or light (p = 0.017). At day 2, the profile of pain moderate/severe was more prevalent for patients who had surgery in the mandible (p < 0.001) with the report of difficult surgery (p = 0.042) and with odontotomy performed (p = 0.033). In the third postoperative day, severe/moderate pain was associated with surgery in the mandible (p < 0.001) and with odontotomy (p = 0.021) and ostectomy (p = 0.028) performed, with report of long and difficult procedure (p = 0.023), surgeries which last more than sixty minutes (p < 0.026), and for those patients who developed postoperative inflammatory complications (p < 0.001).
Conclusion:
Higher pain complains could be expected for patients who have long and difficult mandibular third molar surgery characterized by odontotomy and ostectomy.
Clinical Significance:
Pain after third molar surgery is a common sequele. It is indispensable for the dentists to be apt in handling and preventing it as far as possible and know possible variables that may influence or increase these pain levels. It can be a clinical advantage. Better understanding the pain characteristics may guide the dentist through preoperative decisions.
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