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Updated: Feb 17, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Optical coherence tomographic features in a case of bilateral macular coloboma with strabismus
Shengli Hao1, Zhiheng Liu, Yanshan Xu
1Department of Ophthalmology, Affiliated Hospital of Tianjin Medical University, Tianjin, China. taishanmaple@126.com
Purpose:
To report the optical coherence tomography (OCT) findings in a patient with bilateral macular coloboma with strabismus.
Methods:
A 21-year-old male presented with macular coloboma in both eyes.Fundus photography, fundus fluorescence angiography (FFA) and OCT were performed.
Results:
Color fundus photography showed a sharply-demarcated, round macular defect, approximately 4×4 disc diameters with bare sclera at the base and pigment clumping in both eyes. FFA showed hypofluorescence at the macula corresponding to the size of the lesion bilaterally. OCT revealed a crater-like depression at the macula, demonstrating atrophic neurosensory retina, and an absence of retinal pigment epithelium (RPE) and choroid in the lesion.
Conclusion:
OCT can be a beneficial tool to confirm the diagnosis of macular coloboma.

