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Updated: May 26, 2026

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
Published on: May 14, 2020
Revision of a tibial baseplate using a customized oxinium component in a case of suspected metal allergy. A case
Nick Van Opstal1, Frank Verheyden
1Department of Orthopaedic Surgery, Heilig Hart Hospital, Lier, Belgium. nick.vanopstal@hotmail.com
Abstract:
Materials currently used for total knee arthroplasty (TKA) are well known for their good biocompatibility, but corrosion of the implant and metal ion release may elicit an immune response in the periprosthetic tissue. Its role in the outcome of the implant remains a subject of discussion. Metal sensitivity after joint replacement is frequent, but few patients exhibit symptoms. Nickel, cobalt and chromium are the most common sensitizers, but allergic reactions to titanium and vanadium have also been described. We present a case of a 46-year old woman with persistent dermatitis following TKA revision with an oxidized zirconium (oxinium) femoral component and Ti6Al4V tibial baseplate. After revision with a customized oxinium tibial component, symptoms resolved completely.

