Related Experiment Video
Updated: May 26, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood
Published on: April 28, 2016
Regulating satiety in bulimia nervosa: the role of cholecystokinin
1Psychiatric/Mental Health Department, Connell School of Nursing, Boston College, Chestnut Hill, Massachusetts, USA. hannonen@bc.edu
Purpose:
Individuals with bulimia nervosa (BN) report altered perceptions in hunger, fullness, and satiety. This article reviews the role of cholecystokinin (CCK), a satiety-producing hormone, in the regulation of binge eating in those who suffer from BN.
Conclusion:
Studies have shown that CCK is decreased in individuals with BN when compared with healthy controls. Decreased CCK functioning may contribute to impaired satiety and thus binge eating in this patient population. Depending on the macronutrient composition of food choices, CCK release can be differentially influenced. For instance, protein is a potent stimulator of a CCK response. Eating more protein-rich meals increases the release of CCK, increasing satiety and ending a meal.
Practice Implications:
Knowledge of CCK functioning and the utility of manipulating the macronutrient composition of meals may inform standard behavioral treatment strategies for those who suffer from BN.
Related Concept Videos
Regulation of Food Intake
Bulimia Nervosa
Hormonal Regulation
Binge Eating Disorders
Neural Regulation
Cholecystitis

