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Lung mast cells and hypoxic pulmonary hypertension

H Maxová1, J Herget, M Vízek

  • 1Department of Pathophysiology, Second Faculty of Medicine, Charles University in Prague, Prague, Czech Republic. hana.maxova@lfmotol.cuni.cz

Physiological Research
|December 23, 2011
PubMed
Summary

Hypoxic pulmonary hypertension involves increased pulmonary vascular tone and arterial remodeling. Mast cells contribute to this condition by releasing factors that mediate tissue destruction and remodeling during hypoxia.

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