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Cerebral cysticercosis.

S Y Yang1, M L Wang, Q C Xue

  • 1Department of Neurosurgery, Tianjin Medical College Hospital, People's Republic of China.

Surgical Neurology
|November 1, 1990
PubMed
Summary
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Cerebral cysticercosis, a parasitic brain infection, can cause hydrocephalus and intracranial hypertension. Early diagnosis via CT scans and serological tests aids in managing this serious neurological condition.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Cerebral cysticercosis is a significant parasitic infection of the central nervous system.
  • It can lead to severe neurological complications including hydrocephalus and increased intracranial pressure.

Purpose of the Study:

  • To analyze the clinical presentation, diagnosis, and management of cerebral cysticercosis.
  • To evaluate diagnostic methods and treatment outcomes over a 30-year period.

Main Methods:

  • Retrospective review of 143 cerebral cysticercosis cases from a 30-year period.
  • Comparison of diagnostic techniques including pneumoencephalography, ventriculography, and computed tomography (CT).
  • Assessment of serological tests: complement fixation test (CFT) and enzyme-linked immunosorbent assay (ELISA) in serum and cerebrospinal fluid (CSF).

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Main Results:

  • Hydrocephalus occurred in 46 cases, while 97 had cerebral parenchymal cysts.
  • CT scans demonstrated typical abnormalities in 25 out of 28 examined cases.
  • ELISA showed high positivity rates (90% serum, 92% CSF), superior to CFT (74% serum, 73% CSF).
  • Surgical intervention for hydrocephalus and medical management for intracranial hypertension were employed.
  • Mortality was 11% in the acute stage and an additional 20% at follow-up.

Conclusions:

  • Computed tomography has become the primary diagnostic tool for cerebral cysticercosis.
  • ELISA is a highly sensitive method for diagnosing cysticercosis.
  • Management strategies involve surgical and medical interventions, with significant associated mortality.