Management of children with inherited mild bleeding disorders undergoing adenotonsillar procedures

Raimundo García-Matte1, M María Constanza Beltrán, A Ximena Fonseca

  • 1Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Insights

A perioperative bleeding prophylaxis protocol significantly reduced bleeding rates in children with mild bleeding disorders undergoing adenotonsillar surgery. This highlights the importance of timely diagnosis and tailored interventions for safer surgical outcomes.

Area of Science:

  • Pediatric Surgery
  • Hematology
  • Anesthesiology

Background:

  • Adenotonsillar surgery is common in children.
  • Mild bleeding disorders can increase surgical risks.
  • Effective perioperative management is crucial for patient safety.

Purpose of the Study:

  • To evaluate the incidence of perioperative bleeding in children with mild bleeding disorders undergoing adenotonsillar surgery.
  • To assess the effectiveness of a specific perioperative bleeding prophylaxis protocol.

Main Methods:

  • Retrospective chart review of 44 children with mild bleeding disorders (Low von Willebrand factor, unspecific platelet function disorders, mild factor VII deficiency).
  • Protocol included intravenous desmopressin, tranexamic acid, NSAID avoidance, and overnight observation.
  • Adenotonsillar procedures were performed between 2004 and 2009.

Main Results:

  • Only one patient (2.3%) experienced perioperative bleeding.
  • The patient who bled had combined Low von Willebrand factor and unspecific platelet function disorders.
  • The protocol demonstrated a low bleeding rate in this cohort.

Conclusions:

  • Low rates of perioperative bleeding are achievable in children with mild bleeding disorders undergoing adenotonsillar procedures.
  • A well-timed diagnosis and an adequate prophylaxis protocol are essential for safe surgical outcomes.
  • Further research should focus on improving preoperative diagnosis of mild bleeding disorders to enhance surgical safety.
Abstract

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