Frequency of peripherally inserted central catheter complications in children

Angela Barrier1, Derek J Williams, Megan Connelly

  • 1Division of Hospital Medicine, Department of Pediatrics, Vanderbilt University School of Medicine and the Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, TN 37232, USA.

Insights

Complications occurred in over 30% of peripherally inserted central catheters (PICCs) in pediatric patients receiving antimicrobial therapy. Risk factors included double-lumen lines, femoral placement, younger age, and more frequent dosing.

Area of Science:

  • Pediatric medicine
  • Vascular access devices
  • Infectious disease management

Background:

  • Peripherally inserted central catheters (PICCs) are crucial for long-term intravenous access in pediatric patients, particularly for antimicrobial therapy.
  • Complications associated with PICCs can lead to treatment delays, increased healthcare costs, and patient morbidity.
  • Understanding the incidence and risk factors for PICC complications is essential for optimizing patient care.

Purpose of the Study:

  • To determine the frequency and types of complications associated with PICCs in immunocompetent pediatric patients undergoing parenteral antimicrobial therapy.
  • To identify specific risk factors that contribute to the occurrence of PICC-related complications in this population.

Main Methods:

  • Retrospective analysis of pediatric patients who received PICCs for parenteral antimicrobial therapy.
  • Data collection on PICC placement, duration, complications, and patient demographics.
  • Statistical analysis to calculate complication frequency and identify associated risk factors.

Main Results:

  • Complications occurred at a rate of 19.3 per 1000 PICC days.
  • Over 30% of placed PICCs experienced at least one complication.
  • Identified risk factors included double-lumen PICCs, femoral vein placement, younger patient age, and a higher number of daily medication doses.

Conclusions:

  • PICC complications are frequent in pediatric patients receiving antimicrobial therapy, necessitating careful monitoring and management.
  • Specific factors such as catheter design, insertion site, patient age, and dosing frequency are associated with increased complication risk.
  • These findings can inform clinical practice to minimize PICC-related adverse events in pediatric populations.

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