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Related Experiment Video

Updated: May 26, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Radiation therapy for liver metastases.

Alejandra Mendez Romero1, Morten Høyer

  • 1Department of Radiation Oncology, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands. a.mendezromero@erasmusmc.nl

Current Opinion in Supportive and Palliative Care
|December 23, 2011
PubMed
Summary

Stereotactic body radiation therapy (SBRT) and whole-liver radiation therapy (WLRT) are effective for liver metastases. SBRT treats limited disease, while WLRT palliates diffuse infiltration, though more trials are needed.

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Area of Science:

  • Oncology
  • Radiation Oncology
  • Hepatology

Background:

  • Liver metastases are common, often managed with systemic therapy.
  • Surgical or ablative approaches are options for limited disease.
  • Radiation therapy technology has advanced, enabling precise high-dose delivery.

Purpose of the Study:

  • To review recent literature on stereotactic body radiation therapy (SBRT) for liver metastases.
  • To update knowledge on whole-liver radiation therapy (WLRT) for palliative care in liver metastases.

Main Methods:

  • Review of recent scientific literature on SBRT and WLRT for liver metastases.
  • Analysis of treatment efficacy and toxicity from published studies.

Main Results:

  • SBRT is highly effective for ablating liver metastases with mild to moderate toxicity.
  • SBRT is indicated for patients with limited intrahepatic and extrahepatic disease.
  • Low-dose WLRT effectively palliates symptoms in patients with diffuse liver metastases refractory to systemic treatment.

Conclusions:

  • SBRT and WLRT demonstrate high efficiency in managing liver metastases.
  • Further prospective randomized trials are necessary to solidify the role of radiation therapy in liver metastases.