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Related Concept Videos

Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...
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Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
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Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
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REM Sleep Behavior Disorder01:15

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Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
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Related Experiment Video

Updated: May 26, 2026

Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis
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Published on: June 10, 2022

Parry-romberg syndrome: a rare entity.

Hiren Patel, Chintan Thakkar, Kajal Patel

    Journal of Maxillofacial and Oral Surgery
    |December 23, 2011
    PubMed
    Summary

    Parry-Romberg syndrome, or progressive hemifacial atrophy, is a rare degenerative condition causing slow facial tissue loss. Treatment involves a multidisciplinary approach after the condition stabilizes.

    Keywords:
    En coup de sabreLocalized linear sclerodermaParry–Romberg syndromeProgressive hemifacial atrophyRomberg’s Sign

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    Published on: March 23, 2022

    Area of Science:

    • Medical Science
    • Dermatology
    • Neurology

    Background:

    • Parry-Romberg syndrome (PRS), also known as progressive hemifacial atrophy, is an uncommon degenerative condition.
    • It is characterized by slow, progressive tissue loss affecting one side of the face.
    • The exact incidence and causes of PRS remain poorly understood.

    Purpose of the Study:

    • To conduct a comprehensive literature review on Parry-Romberg syndrome.
    • To detail the general characteristics, etiology, and pathophysiology of progressive hemifacial atrophy.
    • To outline differential diagnoses and current treatment strategies for PRS.

    Main Methods:

    • Literature review of existing studies on Parry-Romberg syndrome.
    • Analysis of reported cases to identify common features and potential causes.
    • Synthesis of information regarding diagnostic criteria and therapeutic interventions.

    Main Results:

    • PRS is a rare condition with unknown etiology, possibly linked to fat metabolism, trauma, infections, genetics, or autoimmunity.
    • Common complications include trigeminal neuritis, facial paresthesia, severe headaches, and epilepsy.
    • Facial atrophy progresses slowly over years before stabilizing.

    Conclusions:

    • A multidisciplinary approach is essential for managing PRS.
    • Treatment strategies, including orthodontic interventions and reconstructive surgery with autogenous fat grafts, are considered after disease stabilization.
    • Further research is needed to elucidate the pathogenesis and improve treatment outcomes for progressive hemifacial atrophy.