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Updated: May 26, 2026

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Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
Published on: February 21, 2016
[Optimization of kidney transplantation from elderly donors]
Vestnik Khirurgii Imeni I. I. Grekova
|December 24, 2011
Summary
Kidney transplants using expanded criteria donors are effective for older adults (60-76 years). This study shows satisfactory outcomes, with creatinine levels improving significantly by 90 days post-transplant.
Area of Science:
- Nephrology
- Transplant Surgery
- Geriatric Medicine
Context:
- Kidney transplantation is a vital treatment for end-stage renal disease.
- Utilizing expanded criteria donors (ECDs) can increase donor pool availability.
- Older adult recipients present unique physiological considerations for transplantation.
Purpose:
- To evaluate the outcomes of kidney transplantation in elderly recipients using ECDs.
- To assess the efficacy of standard and dual renal transplantation in this demographic.
Summary:
- Twenty-seven elderly patients (60-76 years) received kidney transplants from ECDs.
- Twenty underwent standard transplantation, while seven received dual renal transplants.
- Mean creatinine levels showed significant improvement from 340.9 +/- 49.3 microM/l at day 21 to 124.6 +/- 6.9 microM/l at day 90.
Impact:
- Demonstrates the viability and success of ECD kidney transplants in older populations.
- Provides evidence for improved renal function in elderly transplant recipients.
- Supports the expanded use of ECDs to address organ shortages in kidney transplantation.
Related Concept Videos
Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

