Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Ultrasonography01:17

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimization of Covalent Warhead Trajectory for KRAS<sup>G12C</sup> Active-State Inhibition.

Journal of medicinal chemistry·2026
Same author

Optimization of α-Fluoro, β-Heteroaryl Acrylamide Warheads for KRAS<sup>G12C</sup> Active-State Inhibition.

Journal of medicinal chemistry·2026
Same author

Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C.

Nature communications·2026
Same author

An orthogonal methods assessment of topical drug concentrations in skin and the impact for risk assessment in the viable epidermis.

Regulatory toxicology and pharmacology : RTP·2021
Same author

Evidence for the Validity of Pyridoxic Acid (PDA) as a Plasma-Based Endogenous Probe for OAT1 and OAT3 Function in Healthy Subjects.

The Journal of pharmacology and experimental therapeutics·2018
Same author

Synergistic inhibition of Aβ production by combinations of γ-secretase modulators.

European journal of pharmacology·2017
Same journal

A simple, sensitive microsample LC-MS assay for quercetin and isorhamnetin in mouse and human plasma: application to EMIQ treatment in myotonic dystrophy type 1.

Bioanalysis·2026
Same journal

ADA assays for high-dose biologics: redefining drug tolerance through clinical insights.

Bioanalysis·2026
Same journal

Comparison of SERS spectral data sets of blood serum samples of hypopharyngeal cancer using silver and gold nanoparticles as substrates.

Bioanalysis·2026
Same journal

The Gyrolab platform for immunogenicity assessment and biotherapeutic and biomarker analysis: technical advances and bioanalytical applications.

Bioanalysis·2026
Same journal

Simultaneous quantification of D-penicillamine, D-penicillamine disulfide, and L-cysteine-D-penicillamine disulfide in human plasma: optimization of sample preparation and mass spectrometry procedures to support bioequivalence studies.

Bioanalysis·2026
Same journal

Development and preliminary clinical application of a time-resolved fluoroimmunoassay for anti-rituximab antibodies in membranous nephropathy.

Bioanalysis·2026
See all related articles

Related Experiment Video

Updated: May 26, 2026

Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples
06:47

Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples

Published on: June 29, 2022

Tissue analysis by imaging MS.

Stacey R Oppenheimer1, Dieter M Drexler

  • 1World Wide Medicinal Chemistry, Pfizer Global Research & Development, Eastern Point Road, Groton, CT 06340, USA. stacey.oppenheimer@pfizer.com

Bioanalysis
|December 24, 2011
PubMed
Summary
This summary is machine-generated.

Imaging Mass Spectrometry (IMS) offers powerful chemical analysis of intact tissues. This review explores diverse IMS platforms and their biomedical and pharmaceutical applications.

More Related Videos

Imaging of Biological Tissues by Desorption Electrospray Ionization Mass Spectrometry
06:21

Imaging of Biological Tissues by Desorption Electrospray Ionization Mass Spectrometry

Published on: July 12, 2013

Related Experiment Videos

Last Updated: May 26, 2026

Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples
06:47

Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples

Published on: June 29, 2022

Imaging of Biological Tissues by Desorption Electrospray Ionization Mass Spectrometry
06:21

Imaging of Biological Tissues by Desorption Electrospray Ionization Mass Spectrometry

Published on: July 12, 2013

Area of Science:

  • Analytical Chemistry
  • Biomedical Research
  • Pharmaceutical Science

Background:

  • Mass spectrometry (MS) advances enable new insights into chemical and biological processes.
  • Imaging Mass Spectrometry (IMS) provides unparalleled chemical analysis of intact tissue.
  • Significant scientific interest is driven by IMS's capabilities.

Purpose of the Study:

  • To review various Imaging Mass Spectrometry (IMS) platforms.
  • To discuss the applications of IMS in biomedical research.
  • To highlight the utility of IMS in pharmaceutical research.

Main Methods:

  • Literature review of IMS platforms.
  • Analysis of IMS applications in published studies.
  • Synthesis of information on IMS technology and its uses.

Main Results:

  • Overview of different IMS technologies available.
  • Examples of IMS applications in disease research and drug development.
  • Demonstration of IMS's value in spatial chemical analysis.

Conclusions:

  • IMS is a rapidly advancing field with broad applicability.
  • Various IMS platforms cater to specific analytical needs.
  • IMS significantly contributes to biomedical and pharmaceutical research advancements.