Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stroke and its modification in Parkinson's disease.

L K Struck1, R L Rodnitzky, J K Dobson

  • 1Department of Neurology, University of Iowa College of Medicine, Iowa City.

Stroke
|October 1, 1990
PubMed
Summary

Parkinson's disease patients have a lower incidence of ischemic stroke and myocardial infarction. This may be linked to reduced atherosclerosis, potentially due to lower tobacco use and possibly dopamine deficiency.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thalamic ependymoma presenting as recurrent subarachnoid hemorrhage.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015
Same author

Driving with distraction in Parkinson disease.

Neurology·2006
Same author

Visual dysfunction in Parkinson disease without dementia.

Neurology·2005
Same author

Neuropathology of two members of a German-American kindred (Family C) with late onset parkinsonism.

Acta neuropathologica·2002
Same author

Visual dysfunction in Parkinson's disease.

Clinical neuroscience (New York, N.Y.)·2000
Same author

Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-responsive cervical dystonia.

Neurology·1999

Area of Science:

  • Neurology
  • Epidemiology
  • Cardiovascular Disease

Background:

  • Conflicting previous studies on ischemic stroke incidence in Parkinson's disease (PD).
  • PD presents unique epidemiologic and neurochemical factors potentially influencing stroke risk.
  • Investigating the relationship between PD and cerebrovascular/cardiovascular events is crucial.

Purpose of the Study:

  • To determine the lifetime incidence of ischemic stroke in Parkinson's disease patients compared to controls.
  • To assess myocardial infarction incidence as a marker for generalized atherosclerosis.
  • To analyze stroke risk factors in relation to Parkinson's disease.

Main Methods:

  • Case-control study design.
  • Inclusion of 200 Parkinson's disease patients and 200 age-matched controls.

Related Experiment Videos

  • Assessment of lifetime history of ischemic stroke, myocardial infarction, and stroke risk factors.

    • Main Results:

    • Significantly lower cumulative incidence of ischemic stroke in PD patients versus controls.
    • Significantly lower cumulative incidence of myocardial infarction in PD patients.
    • Lower prevalence of tobacco use observed among PD patients.

    Conclusions:

    • Reduced ischemic stroke and myocardial infarction incidence in PD patients.
    • Potential protective effect linked to less severe atherosclerosis, possibly due to lower tobacco consumption.
    • Further research needed to explore potential neuroprotective roles of dopamine deficiency in PD against ischemic stroke.