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Published on: January 7, 2019
A mini review of nanosuspensions development
Yue Liu1, Pengcheng Xie, Dianrui Zhang
1Department of Pharmaceutics, College of Pharmacy, Shandong University, Jinan, PR China.
Journal of Drug Targeting
|December 24, 2011
Summary
Nanosuspension drug delivery enhances the dissolution and solubility of insoluble drugs. This review covers preparation, stability, features, administration, and future directions for nanosuspensions.
Area of Science:
- Pharmaceutical Technology
- Nanotechnology
- Drug Delivery
Background:
- Nanosuspension technology is crucial for formulating insoluble drugs.
- It offers enhanced dissolution rates and saturation solubility.
- Distinguishing nanosuspensions from nanocrystals is essential.
Purpose of the Study:
- To review and compare nanosuspension preparation techniques.
- To discuss stability measures and unique features of nanosuspensions.
- To explore administration routes and future perspectives.
Main Methods:
- Literature review of nanosuspension technology.
- Comparison of different preparation methods.
- Analysis of stability and administration strategies.
Main Results:
- Nanosuspensions significantly improve drug properties for insoluble compounds.
- Various techniques exist for nanosuspension production and stabilization.
- Diverse administration routes are feasible, with ongoing development.
Conclusions:
- Nanosuspensions are a promising approach for poorly soluble drugs.
- Further research is needed to address existing limitations.
- The technology holds significant potential for future drug delivery systems.
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