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Updated: May 26, 2026

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Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
Published on: October 18, 2011
A practical technique to avoid the hippocampus in prophylactic cranial irradiation for lung cancer
Zdenko van Kesteren1, José Belderbos, Marcel van Herk
1Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. z.vankesteren@amc.uva.nl
Abstract:
A practical technique is presented to deliver hippocampus avoiding prophylactic cranial irradiation for lung cancer patients, using two lateral fields. For a prescribed dose of 12×2.5 Gy, sparing of the hippocampi to 6.1 Gy was achieved with a V95% of the brain of 81.7%.

